![]() Yes, Wellbutrin can cause anxiety, but the risk of developing a side effect from Wellbutrin is roughly the same as the risk posed by other antidepressants.Īll antidepressants can cause anxiety, with roughly 1 in 10 depressed patients experiencing this side effect. This is because Wellbutrin has a reputation⁶ for inducing anxiety rather than treating it. There is a little confusion about how Wellbutrin can treat anxiety. The study found that bupropion demonstrated well-tolerated anxiety-reducing results similar to the anxiety treatment provided by escitalopram. The study compared the effectiveness of bupropion to escitalopram, an SSRI used to treat depression and anxiety in patients with generalized anxiety disorder. ![]() However, there is a pilot control study⁵ that has shown promise. More research evaluating the use of Wellbutrin for specific anxiety disorders (an off-label use) is needed to understand its anxiety-reducing potential. Further studies have also concluded that bupropion can have significant anti-anxiety effects⁴ in patients with clinical depression. This is because bupropion has been shown to be effective in reducing the symptoms of depression-related anxiety³. More recent clinical data has found that bupropion (Wellbutrin) is an appropriate treatment option for depressed patients with comorbid anxiety. These results were similar to those seen in comparison groups given sertraline ( Zoloft), an antidepressant commonly used in the treatment of anxiety. One study², in particular, found that bupropion significantly improved anxiety scores in patients. While Wellbutrin is typically used in the treatment of depression, research tells us that it can help to reduce anxiety.
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